Seeking a cure for bladder cancer in Scottish Terriers

With the American Kennel Club Canine Health Foundation funding the work, Deborah Knapp, a Purdue University professor of veterinary medicine and a veterinary medical oncologist, and her group have teamed up with Larry Glickman, a professor of epidemiology and environmental medicine, and Dr. Elaine Ostrander at the National Institutes of Health to research dogs at risk for developing urinary bladder cancer or transitional cell carcinoma.

The research group collects blood samples from dogs that go to Purdue University Veterinary Teaching Hospital such as Scottish terriers and other “at risk” breeds. They also collect blood from older Scottish terriers that do not have TCC.

“These blood samples are then shipped to Dr. Ostrander for whole genome scanning, a process that will enable us to determine the differences in the DNA between dogs with cancer and dogs without cancer,” she said. “It is likely that these differences will reveal genetic factors involved in TCC risk.”

Knapp said they have identified some regions of the DNA that is different between dogs with cancer and dogs without cancer.

See Scottie News‘ previous coverage of this dog cancer research.

8 thoughts on “Seeking a cure for bladder cancer in Scottish Terriers

  1. My name is Rachel and I live in California. I have sent a blood sample to her from my 12 year old that does NOT have cancer. They are using hers and other samples to help fight this disease. Please send yours in today. Your vet may not charge you since it is for research.

  2. My sister-in-law and her husband are human parents of Angus, a wonderful 8-year old Scottie. Today they got a terrible diagnosis from a clinic in Bowie, Maryland where their family Vet referred them that Angus has a very fast growing, aggressive kind of cancer that was only a few non-specific symptoms a couple of weeks ago. They are taking him home this afternoon from the clinic in Bowie and will have a quiet evening at home with their boy before having the their Vet come in tomorrow around nine to help him on his journey into the spirit world.

    Joe (my sister-in-law’s husband) is Angus’s personal human. He likes Kathy well enough but the sun rises and sets for Angus on Joe. For Joe it is the same if not even more. The love these two have for each other is a wonderful thing to see and the grief Joe has to bear up under now is just enormous.

    My wife and I (it is her sister) have two Scotties now and have had three others over the years and we are just grief stricken with this news. This little guy is just the best Scottie, friendly, playful, caring…

    Please give a thought today to Angus, Joe, and Kathy.


    1. I am so sorry to hear this. We have 2 rescue scotties, brother & sister… Rosie has just been diagnosed with cancer of the bladder, we are devastated as we have had such a short time with them. They are 10 and litter mates, Archie will be totally lost without her. She is on peroxicam and have another scan in the 24th November to see how this is working. We live in Yorkshire, although I am Scottish. They are my world

  3. So sorry to hear that Terry.

    Dogs have short enough lives as it is.

    It’s just awful when something like this happens.

    My sympathies to Joe and Kathy.

  4. I just lost my Scottie Shadow on Wednesday to his bladder cancer. He would have been 12 in October. He was diagnosed in February and he had prioxicam and some pain meds but the tumor was aggressive and kept growing. I wish I had another day with him. Give your scotties a hug and take them out for a walk and love on them for me.

  5. My condolences, JCNH! So unfair for our dogs. We had a scare with our Teagan this year, she had a TCCC but fortunately when it was caught it was so small it was removed at biopsy.. still monitoring her and actually your post flags up that she is due for her next test. Thank you very much for your comment despite your pain because I'd missed this original post and now going to look into taking part in this study. And I will also do what you suggested. 🙂

    1. Hi tcmum…

      Just lost our beloved Scottie, Annie to bladder cancer last weekend. She was 10. How has your little one been doing since diagnosis? Almost wondering if it’s worth having an ultrasound done every six months beginning when they’re 9 years old or so.

  6. Our darling 12 year old Angus was diagnosed with bladder cancer in early December, following a vet visit to deal withe some troubling incontinence. He was nonetheless so frisky and happy for all of December and most of January, and then suddenly he declined quickly. In the last week he had gone from playing with his toys and eating robustly, and loving his walkies to laying around, disinterested in food, and then soon afterwards vomiting yellowish bile. We took him in to be put to sleep and just buried him today in some tartan fabric with his favorite toys. We are so deeply saddened and hope he somehow knows how much we love and miss him.

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