With the American Kennel Club Canine Health Foundation funding the work, Deborah Knapp, a Purdue University professor of veterinary medicine and a veterinary medical oncologist, and her group have teamed up with Larry Glickman, a professor of epidemiology and environmental medicine, and Dr. Elaine Ostrander at the National Institutes of Health to research dogs at risk for developing urinary bladder cancer or transitional cell carcinoma.
The research group collects blood samples from dogs that go to Purdue University Veterinary Teaching Hospital such as Scottish terriers and other “at risk” breeds. They also collect blood from older Scottish terriers that do not have TCC.
“These blood samples are then shipped to Dr. Ostrander for whole genome scanning, a process that will enable us to determine the differences in the DNA between dogs with cancer and dogs without cancer,” she said. “It is likely that these differences will reveal genetic factors involved in TCC risk.”
Knapp said they have identified some regions of the DNA that is different between dogs with cancer and dogs without cancer.
See Scottie News‘ previous coverage of this dog cancer research.